Product record

OsteoGen Plug: composition, claims and alternatives

A bone graft plug from Impladent Ltd., combining what the manufacturer calls non-ceramic calcium apatite crystals with a Type I bovine Achilles tendon collagen matrix. Its mineral is chemically unlike most other plugs on the US market: the manufacturer states explicitly that it is not β-TCP, not dense ceramic hydroxyapatite, and not a blend of the two. It is supplied dry in three sizes, and it is radiolucent when placed.

Impladent Ltd.
Non-ceramic calcium apatite
Bovine collagen carrier
Verified 2026-08-21

Specifications

What the manufacturer and its distributors publish

Manufacturer: Impladent Ltd., Jamaica, NY
US distribution: Ultradent Products, and general dental distributors
Category: Mineral-collagen plug
Composition: Non-ceramic calcium apatite crystals in a Type I bovine Achilles tendon collagen matrix
Mineral origin: Synthetic
Mineral percentage: Not published
Collagen source: Bovine (Achilles tendon)
Collagen percentage: Not published
Sizes: 6 × 25 mm (Slim), 10 × 20 mm (Large), 15 × 20 mm (X-Large)
Units per box: 5 or 10, depending on size and distributor
Placement: Delivered dry into the socket and allowed to take up blood
Radiopacity: Radiolucent on placement, becoming radiopaque as it mineralizes
Publicly listed price: Not consistently published

Sizes and pack counts are as listed by US distributors; the manufacturer does not publish a consolidated specification sheet. Mineral and collagen percentages are not published anywhere we could find, which is why those rows are empty rather than estimated.

Against the rest of the category

Three things that set this plug apart

Differences of fact, taken from the published specifications. None of them is a claim that this product performs better or worse than any other.

The mineral is not the one its closest competitors publish

Three of the other synthetic plugs in our database, RegenerOss, REGENAFILL and Straumann SocketPlug, publish a carbonate apatite mineral, and ours publishes a β-TCP and hydroxyapatite blend. Impladent rules both out for this product, describing the mineral as non-ceramic calcium apatite and stating that it is not β-TCP, not a dense ceramic hydroxyapatite, and not a biphasic mixture of the two. Whatever weight a clinician gives that, it is a real chemical distinction rather than a difference in branding.

It is radiolucent when you place it

The manufacturer describes the crystals turning from radiolucent to radiopaque as they mineralize, and treats full radiopacity as the point at which host bone has formed. A graft that does not show on an immediate post-operative radiograph reads differently from one that does, so it is worth knowing before the first time you take one. No other manufacturer in our database publishes radiopacity at placement either way, so we cannot tell you how the rest compare.

The carrier is bovine

The mineral phase is synthetic, and the collagen matrix holding it is bovine Achilles tendon. A patient declining animal-derived material is not accommodated by choosing this product over a xenograft plug. That is true of every mineral-collagen plug in our database, including both of ours.

In the manufacturer's words

What is claimed, and how we read it

Quoted rather than paraphrased, so the claim can be checked against its source.

Resorbable; replaced by host bone tissue in 4 to 6 months.

Ultradent, US distributor product page

Our note The manufacturer’s own brochure publishes 3 to 6 months for the same product. Both figures are current at the time of writing. We report both and adopt neither: human histology of comparable mineral classes finds residual graft particles persisting beyond these windows, and time to implant placement depends on the site and the patient.

The crystals will resorb over 3 to 6 months and will turn from radiolucent to radiopaque. Once fully radiopaque, sufficient host bone has formed and implant placement can now be achieved.

Ultradent, US distributor product page

Our note Radiographic appearance is one input. Bone readiness needs confirming clinically as well as radiographically before an implant goes in, whatever the packaging says.

No need for a membrane. Compact the OsteoGen Plug to make a membrane.

Impladent OsteoGen Plug brochure

Our note Stated without condition. We do not publish the unconditional form of this claim for our own products either. In an intact, contained socket a plug can reasonably be placed as a one-step procedure; where a socket wall is deficient or the defect is not contained, a barrier membrane and standard guided bone regeneration principles still apply. Notably, Geistlich states in print that the collagen in its own graft does not replace a membrane’s barrier function.

We quote these because a clinician comparing products should see the claim as it was made. Quoting is not endorsing: where a claim is unconditional we say so, and we do not publish the unconditional form for our own products either.

Clinical evidence

What the evidence supports, at three different levels

Evidence for the procedure is not evidence for a material class, and neither is evidence for a specific product. These are kept apart on purpose.

Evidence about the procedure

Grafting the socket reduces ridge loss, but does not stop it

A meta-analysis comparing ridge preservation with unassisted socket healing reported roughly 1.3–1.5 mm less bucco-oral width loss and 0.9–1.1 mm less height loss in grafted sites, with implants placed in the planned position without further augmentation at 90.1% of grafted sites against 79.2% of untreated ones. This is evidence about grafting a socket. It is not evidence for any product named on this page.

Evidence about the material classes

No material class is established as superior, and none is fully replaced

Reviews of ridge preservation have not established that any one material class is clinically superior for hard-tissue outcomes. Human histology also indicates that mineral grafts are not fully replaced by the patient’s own bone within the periods studied: roughly 26% residual graft material at around five months for a β-TCP and hydroxyapatite blend, and deproteinized bovine mineral particles described as not resorbed but surrounded by new bone at six months. That bears directly on how to read any manufacturer’s "replaced by host bone tissue" figure, including the ones quoted above.

Evidence about this specific product

Thin, and we are not going to pretend otherwise

We are not aware of published randomized controlled trials establishing outcomes for the OsteoGen Plug specifically. One registered comparative trial was identified, against freeze-dried bone allograft with a collagen barrier; we have not read its results and cannot say what they show. What else exists is manufacturer-published material and clinician case documentation, useful for seeing handling and technique and not the same class of evidence as the reviews above. The same limitation applies to our own two plugs, and we say so on their page too.

ClinicalTrials.gov. OsteoGen Plug vs. Freeze-dried Bone Allograft With Collagen Barrier. NCT06447844.

Evidence about the procedure and about a material class is not evidence about a product. The three tiers above are kept apart for that reason, and the third one is short because the published record is short.

State of the record

What is known, and what is not

Established from published sources

The mineral is a synthetic calcium apatite the manufacturer describes as non-ceramic, and it is distinct from the carbonate apatite and β-TCP/HA minerals used by most competitors.
The carrier is Type I bovine Achilles tendon collagen.
It is placed dry and takes up blood from the socket.
It is radiolucent on placement and becomes radiopaque over time.
Three sizes are distributed in the US, in boxes of five or ten.

Not published, and not estimated

The mineral and collagen percentages. Neither is published, and we will not estimate them from products with a similar description.
A current instructions-for-use document. We worked from manufacturer and distributor pages, which sit one tier below the IFU in our source hierarchy.
A consistent resorption figure. Two of the manufacturer’s own channels publish different windows.
A reliable current US price. Listings we found either gate the price behind a trade login or vary widely between distributors.
Independent published outcomes for this specific product.

Comparable products

What else is in this format

Grouped by what each one shares with the product above, not by preference.

RegenerOss Bone Graft Plug

Same plug format and a synthetic mineral, but a carbonate apatite rather than a non-ceramic calcium apatite. Published as 80% mineral with 20% Type I bovine collagen, in the same two socket sizes.
Straumann SocketPlug

Publishes the same composition, dimensions and pack size as RegenerOss, and the FDA UDI database lists the same company of record for both: Collagen Matrix, Inc.
REGENAFILL Bone Graft Plug

The same published specification from a third brand owner, and the same UDI company of record again.
PreservaRidge Plug

Same 80/20 structure, same two sizes, same UDI company of record. Its brand owner never names the mineral phase, describing it only as having lower crystallinity than hydroxyapatite.
MinerOss X Plug

Same 80/20 structure, different material class: the mineral is bovine cancellous bone rather than a synthetic. Relevant if a xenograft is what is wanted.
Geistlich Bio-Oss Collagen

A collagenated block rather than a plug, at 90% bovine bone mineral with 10% porcine collagen, cut to fit. The most independently studied product in this category, and the only one here using porcine collagen.
SpongeGraft We supply this

Plug format with a synthetic mineral phase, a 60% β-TCP and 40% hydroxyapatite blend, on a bovine Type I collagen carrier. 10 × 20 mm, five per box.
Sponge ZenGraft We supply this

The same plug format and carrier with a deproteinized bovine bone mineral, for cases where slow resorption and long-term volume maintenance are the priority.

Listed because each shares something specific with the product on this page, not because any of them is better. Published reviews have not established that any material class is clinically superior for hard-tissue outcomes. Two of these are ours and are marked.

Sources

Ultradent Products, Inc. distributor of Impladent OsteoGen https://www.ultradent.com/products/categories/surgical/bone-grafting/osteogen-bone-grafts
Impladent Ltd. manufacturer brochure, 2021 https://www.kyda.org/res/uploads/media/Impladent-1-OsteoGen-Plug-Brochure-2021.pdf
Dental Tribune US trade press, manufacturer-sourced https://us.dental-tribune.com/prod/the-osteogen-plug-one-step-bone-grafting-solution-for-socket-preservation-without-a-membrane/
GoldenDent distributor listing https://www.physicsforceps.com/osteogen-plugs-graft
Glidewell Direct distributor listing https://glidewelldirect.com/products/osteogen-plug-large-10-x-20-mm-5-box
ZimVie Dental brand owner https://www.zimvie.com/en/dental/biomaterial-solutions/bone-graft-materials/regeneross-bone-graft-plug.html
Geistlich Pharma AG manufacturer https://www.geistlich.com/en-gb/dental-professionals/bone-substitutes/bio-oss-collagen

Last verified 2026-08-21. Manufacturers change formulations, packaging and published claims without notice. Every value on this page was read from the source listed against it on that date, and confirming current specifications against the instructions for use in the box remains the clinician's call.

Professional use. This page is product information for licensed dental professionals, compiled from the manufacturer’s and its distributors’ published material. It is not clinical advice, and it is not a substitute for the manufacturer’s instructions for use. Implanex does not sell this product. Product names and trademarks are the property of their respective owners.

OsteoGen Plug questions, answered

What is the OsteoGen Plug made of?

The manufacturer describes it as non-ceramic bioactive resorbable calcium apatite crystals in a Type I bovine Achilles tendon collagen matrix, and states specifically that the mineral is not β-TCP, not a dense ceramic hydroxyapatite, and not a biphasic mixture of the two. The mineral and collagen percentages are not published.

Is the OsteoGen Plug synthetic?

Its mineral phase is synthetic. The collagen matrix that carries it is bovine Achilles tendon, so the product as supplied is not free of animal-derived material. That is true of every mineral-collagen plug we have catalogued, including both of ours.

How long does an OsteoGen Plug take to resorb?

The manufacturer publishes two different figures: its US distributor’s page states 4 to 6 months, and its own brochure states 3 to 6 months. We report both and adopt neither. Human histology of comparable mineral classes finds residual graft particles beyond those windows, and time to implant placement depends on the site and the patient.

What are the alternatives to the OsteoGen Plug?

Several plugs share its format with a different mineral: RegenerOss, Straumann SocketPlug, REGENAFILL and PreservaRidge all publish a carbonate apatite mineral with a bovine collagen carrier. MinerOss X Plug uses bovine bone instead. Bio-Oss Collagen is a collagenated block rather than a plug. Our own SpongeGraft and Sponge ZenGraft are plug-format alternatives with a β-TCP/hydroxyapatite and a bovine mineral respectively.

Does the OsteoGen Plug need a membrane?

The manufacturer states that no membrane is needed and describes compacting the plug to form one. That is stated without condition. Our position, which we apply to our own products too, is that a plug can reasonably be placed as a one-step procedure in an intact, contained socket, while a deficient wall or a non-contained defect means a barrier membrane and standard guided bone regeneration principles still apply.